TABLE OF CONTENTS
TABLE OF CONTENTS I
LIST OF FIGURES.III
LIST OF CHARTSV
EXECUTIVE SUMMARY . 1
1.1 OVERVIEW . 1
1.2 RESPONDENT PRACTICE LOCATION. 2
1.3 COMPETING BRANDS 3
1.4 SYNVISC-ONE® SATISFACTION 4
SURVEY HIGHLIGHTS. 5
2.1 RESPONDENT CHARACTERISTICS . 5
2.2 RESPONSE SUMMARY . 6
2.2.1 Synvisc-One® Users 6
2.2.2 Synvisc-One® Non-Users . 6
RESEARCH METHODOLOGY 7
3.1 RESEARCH METHODOLOGY 7
SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY
RESULTS 8
4.1 QUESTION 1: RESPONDENT EXPERIENCE 8
4.1.1 Average Years of Practice 8
4.1.2 Practice Setting 13
4.2 QUESTION 2: PATIENT VOLUME . 17
4.3 QUESTION 3: BRAND PREFERENCE 21
4.3.1 Brand Preference by Doctor. 21
4.3.2 Brand Popularity by Total Patient Volume 21
4.4 QUESTION 4: SYNVISC-ONE® PATIENT PROFILES 25
4.5 QUESTION 5: SYNVISC-ONE® VERSUS OTHER BRANDS. 29
4.6 QUESTION 6: REASONS FOR USING SYNVISC-ONE® 32
4.6.1 Summarized Reasons for Choosing Synvisc-One® 32
4.6.2 Open-Ended Responses for Choosing Synvisc-One® 33
4.7 QUESTION 7: DOCTOR SATISFACTION 36
4.7.1 Current Users 36
4.7.2 Non/Prior Users 37
4.8 QUESTION 8: PATIENT SATISFACTION 41
4.9 QUESTION 9: EXPECTED CHANGE IN USAGE 42
4.9.1 Expected Change in Usage 42
4.9.2 Expected Change in Usage Versus Satisfaction Rating. 46
4.10 QUESTION 10: REASONS FOR EXPECTED DECREASE IN USAGE 48
SURVEY QUESTIONS 50
LIST OF FIGURES
EXECUTIVE SUMMARY 1
SURVEY HIGHLIGHTS 5
RESEARCH METHODOLOGY 7
SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY
RESULTS 8
Figure 4-1: Respondent Practice Experience, U.S., 2010 9
Figure 4-2: Respondent Practice Setting, U.S, 2010 13
Figure 4-3: Respondent Patient Volume, U.S., 2010 17
Figure 4-4: Respondent Brand Preference, U.S., 2010 22
Figure 4-5: Percentage of Respondent Patients Treated per Month by Brand, U.S.,
2010 22
Figure 4-6: New Synvisc-One® Patients, Current Users, U.S., 2010. 26
Figure 4-7: New Synvisc-One® Patients, Prior Users, U.S., 2010. 26
Figure 4-8: Brands Most Frequently Replaced by Synvisc-One®, Current Users, U.S.,
2010 30
Figure 4-9: Brands Most Frequently Replaced by Synvisc-One®, Prior Users, U.S.,
2010 30
Figure 4-10: Reasons for Using Synvisc-One®, Current Users, U.S., 2010 . 32
Figure 4-11: Reasons for Having Previously Chosen Synvisc-One®, Prior Users, U.S.,
2010 33
Figure 4-12: Qualitative Reasons Given for Not Using Synvisc-One®, U.S., 2010 34
Figure 4-13: Doctor Satisfaction with Synvisc-One®, All Current Users, U.S., 2010 36
Figure 4-14: Doctor Satisfaction with Synvisc-One®, Current Users Who Citied
Convenience as a Positive Factor, U.S., 2010 37
Figure 4-15: Doctor Satisfaction with Synvisc-One®, Non/Prior Users, U.S., 2010 37
Figure 4-16: Patient Satisfaction with Synvisc-One®, Current Users, U.S., 2010 41
Figure 4-17: Patient Satisfaction with Synvisc-One®, Prior Users, U.S., 2010 41
Figure 4-18: Expected Change in Frequency of Synvisc-One® Usage Over the Next
Twelve Months, All Current Users, U.S., 2010 . 42
Figure 4-19: Expected Change in Frequency of Synvisc-One® Usage Over the Next
Twelve Months, Current Users who Cited Convenience as a Positive Factor, U.S.,
2010 43
Figure 4-20: Expected Change in Frequency of Synvisc-One® Usage Over the Next
Twelve Months, Prior-Users, U.S., 2010. 43
Figure 4-21: Reasons for Expected Decrease in Synvisc-One® Usage, Current Users,
U.S., 2010 48
SURVEY QUESTIONS 50
LIST OF CHART S
EXECUTIVE SUMMARY 1
Chart 1-1: Hyaluronic Acid Usage Among Survey Respondents, U.S., 2010 1
Chart 1-2: Respondent Location by State, U.S., 2010 2
Chart 1-3: Brand Preference Among Doctors Who Reported Using Synvisc-One®,
U.S., 2010 3
Chart 1-4: Relative Satisfaction Rating Between Current and Prior Users of Synvisc-
One®, U.S., 2010 4
SURVEY HIGHLIGHTS 5
RESEARCH METHODOLOGY 7
SINGLE-CYCLE HYALURONIC ACID VISCOSUPPLEMENTATION SURVEY
RESULTS 8
Chart 4-1: Respondent Practice Experience, Total Respondents, U.S., 2010 10
Chart 4-2: Respondent Practice Experience, Synvisc-One® Users, U.S., 2010 11
Chart 4-3: Respondent Practice Experience, Synvisc-One® Non-Users, U.S., 2010 12
Chart 4-4: Respondent Practice Setting, Total Respondents, U.S., 2010 . 14
Chart 4-5: Respondent Practice Setting, Synvisc-One® Users, U.S., 2010 15
Chart 4-6: Respondent Location by State, U.S., 2010 16
Chart 4-7: Respondent Patient Volume, Total Respondents, U.S., 2010 . 18
Chart 4-8: Respondent Patient Volume, Synvisc-One® Users, U.S., 2010 19
Chart 4-9: Respondent Patient Volume, Synvisc-One® Non-Users, U.S., 2010 20
Chart 4-10: Respondent Brand Preference, U.S., 2010 23
Chart 4-11: Percentage of Respondent Patients Treated per Month by Brand, U.S.,
2010 24
Chart 4-12: New Synvisc-One® Patients, Current Users, U.S., 2010 27
Chart 4-13: New Synvisc-One® Patients, Prior Users, U.S., 2010 28
Chart 4-14: Brands Most Frequently Replaced by Synvisc-One®, Current Users, U.S.,
2010 31
Chart 4-15: Reasons for Using Synvisc-One®, Current Users, U.S., 2010 35
Chart 4-16: Doctor Satisfaction with Synvisc-One®, Current Users, U.S., 2010 38
Chart 4-17: Doctor Satisfaction with Synvisc-One®, Prior Users, U.S., 2010 . 39
Chart 4-18: Years of Practice Versus Doctor Satisfaction with Synvisc-One®, All
Users, U.S., 2010 40
Chart 4-19: Expected Change in Frequency of Synvisc-One® Usage Over the Next
Twelve Months, Current Users, U.S., 2010 44
Chart 4-20: Expected Positive Change in Frequency of Synvisc-One® Usage Over the
Next Twelve Months, Current Users, U.S., 2010 45
Chart 4-21: Expected Change in Frequency of Synvisc-One® Usage Over the Next
Twelve Months Compared to Synvisc-One® Satisfaction Rating, U.S., 2010 47
Chart 4-22: Reasons for Expected Decrease in Synvisc-One® Usage, Current Users,
U.S., 2010 49
SURVEY QUESTIONS 50